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Being well and happy is good for your health and prolongs your life. Emotions have also a powerful impact on our appearance. A range of emotions—and the ability to express them—are what make you human and beautiful.

It's true. When you're happy, you tend to feel positive, radiant and joyful. Tatchme® Anti-Aging Skin Care believes that emotions have a strong impact our beauty and that our sense of smell is very powerful.  As the journey to the source of wellbeing, Tatchme® has enriched its rejuvenating skin creams with two natural essential oils. Discover our product lines now!

We've heard the expression “you are what you eat” and in this article we explain you what to eat to feel good. If you find yourself cranky, tired and even clinically depressed, you may be able to boost your mood by changing what you eat and when you eat.

Comfort food doesn’t have to mean macaroni and cheese and cookie dough. Dig into these 5 "pick-me-up" foods packed with ingredients to increase energy, decrease anxiety or simply put a smile on your face.


salmonA study in the journal Nutrition found that women with the highest intakes of EPA and DHA—two omega-3 fats found in fish such as salmon, trout and sardines—were less likely to experience symptoms of depression. Omega-3s help promote proper functioning of the neurotransmitters that regulate mood, scientists say. Natural sources include salmon, mackerel, herring and sardines. And because fat is satiating, omega-3s curb hunger for hours. Also, the special essential fatty acids and antioxidants in salmon give skin a remarkable suppleness, radiance and youthful glow.




vitamin DA 2010 study in the International Archives of Medicine found that you're more likely to be bummed out if you are vitamin D deficient. Vitamin D is a precursor to the hormone serotonin, also known as the “happiness hormone,” for its association with mood regulation and relaxation. The primary source of vitamin D is from fortified foods such as milk, juices, breads and breakfast cereals. Short exposure to the sun rays and taking vitamin D supplements also helps in synthesizing and regulating vitamin D in your body.




blueberriesThis "superfruit" is teeming with antioxidants that keep your neural pathways running smoothly, promoting positive energy. New research shows that compounds in the berries help to re-write our genetic code so that the body becomes its own antioxidant factory.

Blueberries boost mood and memory.

Considering their size, berries are pound for pound one of the best anti-aging and longevity promoting foods.  Low in fat and packed with nutrients, you cannot go wrong.




olive oilPeople who ate a Mediterranean-style diet rich in olive oil, nuts, whole grains, fish, legumes, and vegetables were 30 percent less likely to suffer from depression, compared to those who had the lowest Mediterranean diet scores, according to a study the Archives of General Psychiatry. The mix of nutrients in this happy diet can keep your spirits up, scientists say.

Please review our article on the Mediterranean-style diet.




dark chocolateChocolate contains mood-boosting compounds such as theobromine and phenylethyamine. A recent Swiss study found that eating a little over an ounce of antioxidant-rich dark chocolate daily for two weeks reduced stress hormone levels including cortisol in people with high anxiety. Dark chocolate, the richer in cocoa the better, is not only a to-die-for treat; it's actually good for you. And just 1 oz of a very special chocolate packs more than twice the healthy antioxidants punch of red wine or other dark chocolates.

Bonus: dark chocolate is also on this list of the best foods for better sex!


Bon Appétit !



This research is made possible by Tatchme® Natural Beauty, an Italian brand of natural anti-aging face and body creams.  

Please visit our website: www.tatchme.com


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be happy!

Subjective Well-Being (SWB) is how researchers define the individual’s current evaluation of happiness. Such an evaluation is often expressed in affective terms; when asked about subjective well-being, participants will often say, “I feel good”, “I feel happy”.

A  high Subjective Well-Being (SWB) seems to have a direct effect on the health and longevity, making it even increased by 14 percent!!

This is according to Professor Ed Diener, Department of Psychology University of Illinois, who has just published in the Journal of Applied Psychology: Health and Well-Being the most comprehensive review so far of the evidence linking happiness to health outcomes.

Taking into account 160 studies, this review has found "clear and compelling evidence" that -- all else being equal -- happy people tend to live longer and experience better health than their unhappy peers.

"We reviewed eight different types of studies," Diener (nicknamed Dr. Happiness) said. "And the general conclusion from each type of study is that your subjective well-being -- that is, feeling positive about your life, not stressed out, not depressed -- contributes to both longevity and better health among healthy populations."

"I was almost shocked and certainly surprised to see the consistency of the data," Diener said. "All of these different kinds of studies point to the same conclusion: that health and then longevity in turn are influenced by our mood states."

The original article can be found here.


Being Happy Makes you Live Longer and Look Better

So being well and happy is good for your health and prolongs your life. In general, experiencing more positive emotions is a good way of improving SWB. Positive emotions are deep felt emotions like love, joy, gratitude, interest, and hope. While negative emotions close our minds down, positive emotions open them up.

Emotions have also a powerful impact on our appearance. A range of emotions—and the ability to express them—are what make you human and beautiful.

It's true. When you're happy, you tend to feel positive, radiant and joyful.


Tatchme® boosts Positive Emotions with Aromatherapy

A revolutionary anti-aging skincare line, TATCHME® has blended its potent formulas with pure natural essential oils to make you benefit from aromatherapy.

Aromatherapy is the practice of using the natural essential oils extracted from flowers, bark, stems, leaves, roots or other parts of a plant to enhance psychological and physical well-being.

Tatchme® Anti-Aging Skin Care believes that emotions have a strong impact our beauty and that our sense of smell is very powerful.  As the journey to the source of wellbeing, Tatchme® has enriched its rejuvenating skin creams with two natural essential oils.


relax lineTatchme® Relax products are enriched with Hedychium Spicatum essential extract to provide your skin and mind with peace and tranquility. (Green line)   


  Eenrgy LineTatchme® Energy products are enriched with Levisticum Officinale essential oil to provide your skin and mind with vitality and strength. (Orange line)





An apple a day really can help keep the doctor away.

Researchers from Florida State University decided to put apples to the test. Bahram Arjmandi, chair of the department of nutrition, food and exercise sciences at Florida State University in Tallahassee presented the findings at the Experimental Biology meeting in Washington D.C. on April 12, 2011.

They recruited 160 women between the ages of 45 and 65 and randomly assigned them to eat daily servings of either dried apples or prunes, which are dried plums. Study participants received blood tests to look for markers of heart health after 3, 6, and 12 months.


The women who ate apples saw their low-density lipoprotein cholesterol — the "bad" kind known as LDL — drop by 23 percent after six months. At the same time, their "good" high-density lipoprotein cholesterol, or HDL, rose about 4 percent. Women in the apple group ate 2/3 cup each day. Though the apple slices added 240 calories to their daily diet, these women wound up losing weight — 3.3 pounds, on average.

The researchers suggest that two compounds found in apple known as pectin and a class of antioxidants known as polyphenols were behind the heart benefit.



The soluble fibre, pectin, is singled out as one of the most beneficial fibres with unique health-promoting qualities.

Pectins are complex polysaccharides (fibres) present in the cell walls of plants and in the spaces between cell walls. Apples are an excellent source of pectin as they can contain from 10 to 20 percent pectin in dried apple pomace. The peel itself contains 15 percent pectin.


Apple polyphenol are potent antioxidants for scavenging free radicals that are ever present in our bodies. A recent study by the Chinese University of Hong Kong shows that polyphenol extends average lifespan by 10 percent.

When people in the United States consume fruits, 22% of antioxidant compounds come from apples. This makes apples the greatest source of antioxidants in the American diet.

types of apple

Three Easy Tips

  1. Choose organically grown apples whenever possible.
  2. Most of the apple's fiber is contained in its skin. Peeling apples results in the loss of flavonoids and most of its valuable fiber.
  3. Eat the whole fruit instead of simply drinking apple juice, eating peel-free applesauce or taking fiber supplements.



This research is made possible by Tatchme® Natural Beauty, an Italian brand of natural anti-aging face and body creams.  

Please visit our website: www.tatchme.com


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Most people have heard the quote by Fredrich Nietzsche "That which does not kill us makes us stronger." Now there is research to support that assertion.

A study in the Journal of Personality and Social Psychology found that after you face a hardship - like a job loss or the death of a loved one - you're better able to handle tough times in the future. Also, the researchers found that no exposure to negative events may also produce unhappiness.

So remember this whenever a crisis hits: just knowing you'll a come through it better able to roll with the punches can make it easier to cope with.


The Study 

Seery, PhD, assistant professor of psychology at the University at Buffalo and lead author of the study, says previous research indicates that exposure to adverse life events typically predicts negative effects on mental health and well-being, such that more adversity predicts worse outcomes.

But in this study of a national survey panel of 2,398 subjects assessed repeatedly from 2001 to 2004, Seery and co-researchers found those exposed to some adverse events reported better mental health and well-being outcomes than people with a high history of adversity or those with no history of adversity.

"We tested for quadratic relationships between lifetime adversity and a variety of longitudinal measures of mental health and well-being, including global distress, functional impairment, post-traumatic stress symptoms and life satisfaction," Seery says.

"Our findings revealed," he says, "that a history of some lifetime adversity -- relative to both no adversity or high adversity -- predicted lower global distress, lower functional impairment, lower PTS symptoms and higher life satisfaction."

The team also found that, across these same longitudinal outcome measures, people with a history of some lifetime adversity appeared less negatively affected by recent adverse events than other individuals.


waves“Feelings are much like waves, we can’t stop them from coming but we can choose which one to surf.”  Jonatan Mårtensson 


The Important Link Between Emotions and Beauty

Emotions have a powerful impact on our appearance. A range of emotions—and the ability to express them—are what make you human and beautiful. It's true. When you're happy, you tend to feel positive, radiant and joyful.

Thing is, scientific findings show negative emotions can ultimately take a toll on your appearance if you don’t deal with them in a healthy way. So, everyone of us needs to learn to vent, to cope and to repair the damage. Stress can also make you more prone to wrinkles.

The solution? Go laugh your ass off. It instantly neutralizes stress hormones and breaks the stress trance…

Tatchme AppTatchme® has developed a cutting edge smart phones application: The Tatchme® App.  It gives you the opportunity to link your emotions to your beauty regimen in every moment of the day. 

Download it now and enjoy the Tatchme® App!  

When You're Happy and You Know It – You Show It!


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In one of our most popular blog post, we claimed that a cup of coffee a day may help you to look younger and healthier. If you have missed it, please read it here

 We also reported the Harvard Women's Health Watch claiming that moderate coffee consumption, defined as 3 to 4 cups per day, is actually beneficial to your health… Now, new findings come to support this statement.


cup coffeeAccording to a new study published in the journal "Stroke", a publication of the American Heart Association, drinking at least one cup of coffee per day could reduce a woman's risk of stroke by as much as 25%.

Coffee contains large amounts of antioxidants that improve health and is one of the most widely consumed beverages in the world. "Therefore, even small health effects of substances in coffee may have large public health consequences," said Susanna Larsson, Ph.D., lead author of the study and a researcher in the Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institute in Stockholm, Sweden.


“Some women have avoided consuming coffee because they have thought it is unhealthy,” said Dr Larsson.”In fact, increasing evidence indicates that moderate coffee consumption may decrease the risk of some diseases such as diabetes, liver cancer, and possibly stroke.”

The study doesn't prove that coffee lowers stroke risk, only that coffee drinkers tend to have a lower stroke risk. More studies on coffee consumption and stroke are needed before firm conclusions can be reached, Larsson said.

Note:  The study did not differentiate between caffeinated and decaffeinated coffee so these results may apply to both types of coffee consumption.

You can read the abstract of this study at: http://stroke.ahajournals.org/cgi/content/abstract/STROKEAHA.110.603787v1.


This research is made possible by Tatchme®, an Italian brand of natural anti-aging face and body creams.

Please visit our website: www.tatchme.com


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Collagen is one of the most important components in the skin.  It forms deep in the skin and is the primary protein the creates skin structure.  Your skin's appearance depends largely on the amount of collagen and the condition of collagen in the skin. Unfortunately, the amount of collagen produced in the skin decreases as a person gets older.

collagen skin

Keeping (and Replacing) Collagen is the Goal of Almost Every Anti-Aging Product

The primary cell type of the dermis, fibroblasts constitute the layer of the skin below the epidermis (outer layer). These cells generate three main structural components: collagen, elastin, and hyaluronic acid. What we may simply describe as skin "aging" is more specifically this gradual process of thinning as the dermis loses collagen, elastin, and hyaluronic acid.

Collagen, the main component of the dermis, gives it durability. There are actually eighteen types of collagen, eleven of which are present in the dermis.

Elastin gives skin resilience and bounce. Damage to elastin fibers, from sun exposure, age, or disease, leads to a loss of elasticity and, consequently, wrinkles.

Hyaluronic Acid holds water and gives skin volume. In young skin, it is present around and between collagen and elastin cells. As skin ages, though, hyaluronic acid does not play that connective role – which explains the popularity of anti-aging treatments that inject it into the dermis.


The Research

A comprehensive study done at the University of Michigan (2008) indicates that rebuilding collagen through skin treatments aids in anti-aging. This report stresses how collagen-making cells termed fibroblasts are a crucial supporting substance to get younger appearing and more supple skin and that treatments with natural collagen-enhancers facilitated to decrease the appearance of wrinkling because of the stimulation of new collagen creation.
The research concluded that anti-aging collagen enhancing treatments show that they are effective in anti-aging efforts and collagen reduction, which usually starts when people are in their mid-twenties.


Skin Care Myth

There is no way to replace collagen, elastin, or hyaluronic acid with topical treatments. Although you can't replenish collagen, elastin, and hyaluronic acid topically, certain topical products can help stimulate dermal activity. Vitamin C (in the form of ascorbic acid) has been shown to increase collagen production.


collagenTatchme® boosts Collagen with Hematite from Portofino

A revolutionary anti-aging skincare line, TATCHME® combines the vital natural ingredient of hematite with the benefits of aromatherapy. Take a look at our products line

Rich in iron, hematite from Portofino is an essential oligo-element that plays a major role in cell respiration, which promotes an all-day youthful glow.

When applied regularly, scientific studies found that hematite's stimulating action on collagen synthesis fills the wrinkles in-depth, producing a noticeable plumping-up effect on the skin.

"Every women's dream is to have more collagen in their skin" said TATCHME®'s spokesperson Mariel Hemingway


Prevention is Key

The harsh truth is that once wrinkles and fine lines exist, they are hard to minimize.

Sun exposure is the quickest way to degrade the dermis and break down collagen, elastin, and hyaluronic acid. Always wear at least SPF 15 and don't neglect your neck, chest, or hands.

Smoking has been shown to stimulate the breakdown of collagen, while decreasing collagen production by up to 40%. (Another good reason to quit!)

Nutrition is crucial to protecting your body inside and out. Be sure to eat lots of fruits and veggies, while drinking green tea.

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couple sleeping

Beauty sleep is not a myth and sleep does lessen the severity of wrinkles in the face and neck, at least temporarily.


Early in the night-time sleep cycle, people typically have a surge in growth hormone. This period of deep sleep (stages 3 and 4 sleep) contributes to what people call "beauty sleep" as secretion of growth hormone helps repair and rebuild body tissues like muscle and bone. Increased growth hormone release is believed to be linked to the fasting state which develops in human sleep.

There is some evidence that skin cells regenerate faster at night than during the day. Cell division happens throughout the day, but peaks around 2 am. This is literally renewal and rejuvenation during sleep. The peak in cell division happens even if you stay awake at night, while the surge in growth hormone doesn't.


Night-time Beauty Tips

   1.     Apply a Good Night Cream

Sleep does lessen the severity of wrinkles in the neck and face, at least temporarily. Part of this is due to a shift in body position - lying down diverts the force of gravity. But there's more to beauty sleep than that.

During sleep the whole body, including the face, perspires more. This moisture on the skin smoothes out wrinkles. Some cosmetics, like Tatchme® Powerful Anti-Wrinkles Night Cream Relax make your face looks better by making the skin moister while infusing natural anti-wrinkles active.

   2.      Sleep on your back

A website produced by the American Academy of Dermatologists suggests that "resting your face on the pillow in the same way every night for years on end also leads to wrinkles." They suggest sleeping on your back to avoid wrinkles.

   3.      Avoid caffeine after 2PM

Any coffee (or caffeinated tea, soda, energy drink or chocolate bar) after 2 pm will probably disrupt your sleep. Caffeine has a half-life of six hours which means that six hours after your last sip, half the caffeine is still in your body.



sleep for beauty Determine your personal sleep quotient (PSQ)

Pick a bedtime when you're likely to fall asleep quickly, and make sure it's at least eight hours before you need to get up.

Keep to this bedtime for the next week and note when you wake up each morning. If you need an alarm to wake up, if it's difficult to get out of bed or if you're tired during the day, eight hours isn't enough sleep for you. Move your bedtime up by 15 or 30 minutes the next week.

Continue doing this each week until you awaken without an alarm and feel alert all day. When you determine what you think is an ideal bedtime, cut 15 minutes off it to see if you're sleepy the next day. If so, add those 15 minutes back - and you've nailed your PSQ.



The Science Behind

December 2010 - The concept of beauty sleep has acquired some scientific backing, according to a study done by the Karolinska Institute in Stockholm, Sweden. "Our findings show that sleep-deprived people appear less healthy, less attractive,  and more tired compared with when they are well rested," the researchers wrote in a paper published in the BMJ, a British medical journal. "This suggests that humans are sensitive to sleep-related facial cues, with potential implications for social and clinical judgments and behavior."

In February 2011, Professor Francesco Cappuccio from the University of Warwick Medical School in the United Kingdom said the lack of beauty sleep was "a ticking time bomb" for health. Getting less than six hours sleep almost doubles your risk of heart disease!



Get to know more about Tatchme®, natural anti-aging skin care.

We promote a healthy skin care regimen based exclusively on natural, yet effective active ingredients.



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What is it?

Hyaluronic acid is a naturally occurring chemical created by the body that provides cushioning for joints and connective tissues. It is an effective antioxidant and has an incredible ability to bind moisture to tissue.

Hyaluronic acid is present in every tissue of the body, and it performs many important functions. It helps deliver nutrients to and carry toxins from cells that do not have a blood supply, such as those found in cartilage.

Babies skin in full of hyaluronic acid which explains why a baby has such soft and moist skin. As we age the amount of hyaluronic acid in our skin diminishes; we simply produce less of it. With age the level of Hyaluronic acid decreases in the body; that results in wrinkles.


Skin with high hyaluronic acid content             Skin with low hyaluronic acid content

skin with high HA

  skin with low HA
The skin remains hydrated and the surface is supple when the skin contains adequate concentrations of hyaluronic acid.    The skin loses its elasticity and the surface becomes dry, because moisture is lost as hyaluronic acid concentrations decrease.

Beneficial for the Skin

Hyaluronic acid is gaining popularity in the cosmetic and medical industries. Clinical studies have shown that it also helps wounds heal more quickly, and can reduce the appearance of both old and new scars.

Injectible hyaluronic acid fillers, such as Restylane, are being to lessen the appearance of lines, sagging and depressions in the skin caused by acne scars or injury. Hyaluronic acid eventually breaks down and is absorbed in the body, so both cosmetic and medical applications are not permanent. In most cases, the hyaluronic acid augmentation usually lasts between 6-9 months. Repeat treatments will be necessary.

A Skin Care Ingredient

hyaluronic acid gel resized 600Cosmetic products containing hyaluronic acid claim to hydrate the skin, allowing it to appear smoother and more radiant.

Hyaluronic acid is a humectant skincare ingredient which means it draws water to the skin and increases the water content of the epidermis (or outer most layer of the skin). If you are in a humid environment, picture yourself on a tropical island, than a humectant like hyaluronic acid can actually draw water from the atmosphere around you to your skin.

The great thing about hyaluronic acid is that it holds 1,000 times its weight in water. Think of it as a super sponge!

Hyaluronic acid is extremely expensive; it is more than a 1,000 times expensive as glycerin for example, so most topical skincare products don’t contain enough of it in order to be effective over the long-term.


Injections and supplements

Hyaluronic acid is available by injection, but you can also find many oral supplements at health food stores, pharmacies, and online distributorships.

Studies show improvement in for most participants after only 2 to 4 months of oral supplementation, and some patients are able to decrease their dose after the desired results are achieved.


No Serious Side Effects

There have been no serious side effects associated with Hyaluronic acid, although some people find that their skin is irritated at the injection site, and there have been rare reports of oral supplements causing rashes and skin irritation as well.

Use of hyaluronic acid during pregnancy has not been evaluated so far.



Don’t forget – applying hyaluronic acid topically will not replace what your skin has lost as it ages. When applied topically hyaluronic acid simply acts as a great moisturizing agent – nothing more.

It does NOT replace your daily anti-aging skin care regimen. For best result use hyaluronic acid with Tatchme powerful natural anti-wrinkles night cream Energy.


Your Diet: Look for Soy and Starchy Root Foods

Animal products are considered to be the best natural sources of hyaluronic acid.

Soy is a great vegetable option, because of its tendency to increase levels of estrogen in the body--which in turn increases levels of hyaluronic acid. Soy beans in their original baby form are edamame. Tofu, or soy bean curd, is the most versatile soy food. Soy milk, soy ice cream or soy yogurt are a few other options.

A recent study into the benefits of hyaluronic acid focused on the residents of Yazuri Hara, a small village in Japan. Living into their 80s and 90s in very good health, they were smooth skinned and almost wrinkle free. The studied revealed that the starchy root vegetables in their diet enabled their bodies to maintain a high production of hyaluronic acid.

Although there are no known fuirts nor vegetables containing hyaluronic acid nor specific foods that contain hyaluronic acid, some starchy root vegetables, including Satsumaimo (a type of sweet potato), Konyaku (a type of gletanious root), Satoima (a type of sticky potato), have a greater impact on stimulating the body’s natural production of hyaluronic acid.

yuzurihara 07 resized 600




A new survey suggests a trend towards a less “made up” look for US women. Above all, the survey finds women expect their cosmetics to deliver flawless skin and sun protection.

The survey explores the complex relationship American women have with their cosmetics.

The key benefits women want from their cosmetic products and makeup are directly related to beautifying their skin’s appearance.

models without makeup nadia auermanin 0909 de resized 600



  • When asked if they could only own one cosmetic product, over half of young women, 58 per cent, say they want a product that delivers flawless skin tone

  • Although flawless skin tone was the leading response for all women (58 per cent), over half of older women (55+), 51 per cent, report the key benefit they want is to minimize the look of fine lines and wrinkles.

  • Over two-thirds of women, 68 per cent, say they would be willing to give up something for a year to have flawless skin -- even chocolate (51 per cent)!!!


Even as women embrace the natural look, makeup application remains an integral part of many women’s morning routines.  Nearly half, 42 per cent, say if they had to choose between makeup and breakfast when pressed for time before work, they would choose to apply makeup.

Women also recognize the dangers of UV rays and look to their cosmetics to help prevent future skin damage. The majority of women, 56 per cent, say they wear cosmetic products and makeup with SPF protection and older women are more likely to wear SPF cosmetic products and makeup year round, 72 per cent vs. 50 per cent.


Survey Methodology:
Commissioned by Neutrogena Cosmetics, this survey was conducted online within the United States by Harris Interactive from August 9-11, 2010 among 1,018 adult women ages 18 and older.



This research is made possible by Tatchme®, natural anti-aging skin care. We promote a healthy skin care regimen based exclusively on natural, yet effective active ingredients. Discover our creams here http://shop.tatchme.com  


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Research into healthy and slowing aging is now one of the hottest fields in biology.

Last year, geneticists discover a way to extend lifespan of organisms so that humans could conceivably live to be 800 years old! In an amazing development, scientists at the University of Southern California have announced that they've extended the lifespan of yeast bacteria tenfold — and the recipe they used to do it might easily translate into humans. Of course, aging isn't the same in humans and yeast, but it is a pretty significant result.

Scientists dispose of a vast amount of information about the genes and the proteins that influence how long we live. However, the whole scientific debate about aging is uncertainty about its fundamental causes. The original theory that aging was a genetically programmed event has been largely disregarded. If there were an aging gene, we would have seen immortal individuals… but this is not the case.


A new major theory, called “disposable soma”, does not implicate genes but focuses on the idea that cell maintenance is costly and holds that ageing is the lifelong accumulation of random molecular damage.

According to this theory, every living organism must budget its energy among various priorities, including metabolism, growth, activity, and reproduction. Failure to do a perfect job in these maintenance functions leads to an accumulation of damage over the lifetime of the organism.

pom resized 600

Of course genes play a big role in determining a lifespan, because they control the efficiency of our cellular repair process.  The most important damage can be caused by oxidation, which generates “free radicals”, molecules produced by the body that destroy healthy cells.

Scientists seem to have found guardians of the cells that protect them from free radicals. There is an increasingly popular notion that the sirtuins, a class of enzymes, are universal regulators of aging in virtually all living organisms. They represent a prime target for new anti-aging drugs.

These guardians, or sirtuins, are activated by resveratrol, a plant chemical found in grapes, red wine, peanuts, blueberries, pomegranates, dark chocolate and cocoa powder.

Resveratrol is the ingredient in red wine that made headlines in November 2006 when scientists demonstrated1 that it kept overfed mice from gaining weight, turned them into the equivalent of marathoners, and seemed to slow down their aging process.

With its highest concentration in the grape skin, resveratrol, works as an antioxidant polyphenols, counter oxidative damage to human cells and tissues caused by free radicals. Recent studies2 have demonstrated that resveratrol activates a “longevity gene” in yeast that extends life span by 70%. The effects mimic those of calorie restriction, the only proven way of extending maximum life span. Resveratrol activates one of the same “sirtuin (SIR)” genes as calorie restriction.

grapes resized 600

Another natural substance that has been hailed as a potential elixir of life is an enzyme called telomerase. When telomerase is dormant, as it is in most normal adult cells, cells eventually become unstable and die. But when telomerase is active, cells continue living and dividing. This is why scientists believe that preserving telomerase under controlled conditions could possibly lead to new anti-aging therapies. The telomerase activity in the blood can be increased by a healthier lifestyle – taking more exercise, eating more fruit and vegetables and less animal fat. A pilot study3 has revealed for the first time that comprehensive lifestyle changes increase the levels of this enzyme by 30 percent.


Humanity has dreamed for millennia about medicines that extend lifespan. The stated goal of today biotech startup companies4 is to develop medicines that have the same health-boosting effects in people that resveratrol and telomerase had shown in clinical studies.

These companies’ very existence shows that the quest for compounds that slow aging has came from sorcery to the routine process of pharmaceutical development.

Real story.



This research is made possible by Tatchme, an Italian brand of natural anti-aging face and body creams. Please visit our website: www.tatchme.com




1 Resveratrol improves health and survival of mice on a high-calorie diet, Nature 444, 16 November 2006

2 Dr. David A. Sinclair of the Harvard Medical School and Dr. Konrad T. Howitz of Biomol Research Laboratories, August 2003

3 Increased telomerase activity and comprehensive lifestyle changes: a pilot study,  The Lancet Oncology Online September 16, 2008

4 such as Sirtris and Geron.

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